10X CHROMIUM CONNECT SOFTWARE
10X CHROMIUM CONNECT SERIES

558 at 0.6mm, 286 at 1mm, 135 at 1.Apologies if this has been asked before but I didn't find anything.Then, the extracted tissue samples can be used later for various applications at the field of molecular pathology. The instrument can also extract tissue samples to standard 0.2 ml PCR tubes. TMA blocks can be created by combining 0.6, 1, 1.5 and 2 mm diameter tissue cores.The TMA GrandMaster makes possible the screening of whole patient cohorts in just a handful of slides, minimizing costs and time. It enables us to maximize the utility for the spatial technologies available in the STU and minimize costs by combining multiple regions, blocks, samples, and patients on the same slide.Allows the precise selection and extraction of specific regions of interest on the donor blocks and their insertion in recipient blocks.The TMA Grand Master is a fastt, high-capacity and user-friendly tissue microarrayer.Please follow this link for further information

10X CHROMIUM CONNECT SOFTWARE

The platform with SRX software is also capable of performing ORCA (Optical Reconstruction of Chromatin Architecture).Making cultured cells, cell colonies, tissue sections, and entire model organisms accessible for single-molecule localization experiments.

10X CHROMIUM CONNECT SERIES

For thicker specimens, the Vutara allows you to easily perform a Z series and automatically localizes and reconstructs the entire volume.

Proprietary biplane technology, combined with a spatial filter in the emission light path, allows you to acquire 3D data with every acquisition.

Provides easy yet unlimited multiplexed imaging for spatial genomics, transcriptomics, and proteomics.

Achieves depths of >30 μm imaging with proprietary biplane technology.It is combined with Bruker’s microscope fluidics unit, Vutara VXL enables multiplexed imaging for targeted, sub-micrometer multiomics in genomics, transcriptomics, and proteomics research. It supports advanced spatial biology research in extracellular matrix structures, extracellular vesicles (EV), virology, neuroscience, and live-cell imaging. The system enables research on DNA, RNA and proteins, from macromolecular complexes and super-structures, to chromatin structure and chromosomal substructures, to studying functional relationships in genomes and in various subcellular organelles. The Vutara VXL comprehensive biological workstation for nanoscale biological imaging enables super-resolution single-molecule localization microscopy (SMLM) technology in a streamlined system with compact footprint. , Leica Cryostats, Microtomes, and more!) Additional equipment includes Leica Cryostats, Microtomes, freezers (ultra low and low temperature), thermocyclers and 384 qPCRs.Agilent Fragment Analyzer for Library and RNA/DNA/CRISPR quality evaluation.Epredia TMA Grandmaster Automated Tissue Microarrayer.S2 Singulator Automated tissue dissociator (cell and nucleus suspensions).The STU also hosts extensive supportive equipment, including: Nikon Ti2 Eclipse (inverted microscope) with Nikon Elements Software and Large Image Stitching module.Vizgen MERSCOPE (up to 500 genes quantified across a tissue section, sub-cellular resolution).NanoString GeoMx DSP (>18,000 genes or >1,000 proteins quantified on tissue sections/FFPE).

Akoya CODEX (up to 60 antibodies on FFPE/tissue section, single cell resolution).

Akoya Polaris Vectra (up to 9 antibodies on a whole slide (FFPE/frozen tissue), single cell resolution).

Bruker Vutara VXL (super resolution 3D microscopy with spatial tagging and video imaging).

10x Genomics Connect (single cell/nucleus sequencing).

10x Genomics Visium (for FFPE or frozen tissue sections).

In brief the technologies include (click for quick-scroll to the relevant section) The Spatial Technologies Unit (STU) hosts a comprehensive collection of spatial and single cell technologies from 10x Genomics (Visium, Connect), NanoString (GeoMx), Akoya (Polaris Vectra, CODEX), Vizgen (MERSCOPE), and Bruker (Vutara VXL), as well as supportive equipment.

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